Erosive Oral Lichen Planus: A Case Report
Gayathri Suresh *
Department of Oral Medicine and Radiology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, India.
Sindhuja Tamilmani
Department of Oral Medicine and Radiology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, India.
Deivanayagi M
Department of Oral Medicine and Radiology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, India.
Elamparithi Bujabalan
Department of Oral Medicine and Radiology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, India.
Narmadha Chandran
Department of Oral Medicine and Radiology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, India.
*Author to whom correspondence should be addressed.
Abstract
Oral lichen planus is a commonly encountered chronic inflammatory cell mediated immune disease of the oral mucosa, commonly presenting as bilateral white striations known as Wickham's striae, which are often located primarily in atrophic or erosive lesions. Both specific immune responses and non-specific inflammatory pathways are involved in the pathogenesis of this disease. Disruption of physiological immune regulation is thought to be a particularly important factor, which may involve CD40, TNF-α, MMPs, Fas ligand, and mast cell degradation. Treatment options are available, and the course of the condition is often influenced by a number of local and systemic factors. Oral lichen planus is more often diagnosed in female patients as compared to male patients, and diagnosis usually occurs based on clinical findings and histopathological findings, including immunofluorescence and cytology. Some cases show suppression and remission by itself. In this care report, we present a 51-year-old female patient who reported to the Department of Oral Medicine and Radiology diagnosed with oral lichen planus.
Keywords: Oral lichen planus, Wickham's striae, autoimmune disease, immunofluorescence