Paraneoplastic Dermatomyositis with Neurogenic Atrophy Revealing Occult Breast Carcinoma: A Case Report
Tounsi Haifa
Internal Medicine Department, Mohamed Tahar Maamouri hospital Nabeul, Faculty of Medicine of Tunis, Tunisia.
Bouzouaya Hela *
Plastic and Reconstructive Surgery Department, Mohamed Tahar Maamouri hospital, Nabeul, Faculty of Medicine of Tunis, Tunisia.
Abida Houssem
Internal Medicine Department, Mohamed Tahar Maamouri hospital Nabeul, Faculty of Medicine of Tunis, Tunisia.
Sbai Ahmed
Plastic and Reconstructive Surgery Department, Mohamed Tahar Maamouri hospital, Nabeul, Faculty of Medicine of Tunis, Tunisia.
Ben Bahri Mariem
Internal Medicine Department, Mohamed Tahar Maamouri hospital Nabeul, Faculty of Medicine of Tunis, Tunisia.
Mami Haifa
Psychiatry and Mental Illness Department, Mohamed Tahar Maamouri Hospital, Nabeul, Faculty of Medicine of Tunis, Tunisia.
Farhat Emna
Internal Medicine Department, Mohamed Tahar Maamouri hospital Nabeul, Faculty of Medicine of Tunis, Tunisia.
Mohamed Ali Sbai
Plastic and Reconstructive Surgery Department, Mohamed Tahar Maamouri hospital, Nabeul, Faculty of Medicine of Tunis, Tunisia.
Maaroufi Raja
Internal Medicine Department, Mohamed Tahar Maamouri hospital Nabeul, Faculty of Medicine of Tunis, Tunisia.
*Author to whom correspondence should be addressed.
Abstract
Neuromyositis (NM) is a rare and controversial entity. We report the case of a 54-year-old female with no previous pathological history who presented with proximal myalgia. Clinical examination was remarkable for obesity, proximal muscle weakness and left axillary adenopathy. Creatine phosphokinase and lactate dehydrogenase were in the normal range. Anti-nuclear antibodies were positive with anti-Ku positive. Electromyogram was myogenic while biopsy showed DM features with neurogenic atrophy. Investigations revealed breast carcinoma associated with NM. Oral corticosteroid therapy was initiated. A left mastectomy with lymph node dissection followed by chemotherapy then adjuvant radiotherapy was carried out. Progressive improvement was obtained. The identification and collection of cases of NM is useful to improve our knowledge about this rare condition.
Keywords: Neuromyositis, cancer, autoimmune myopathy, dermatomyositis