Histochemistry: Understanding its Principles, Techniques, and their Applications
Josiah Soipiriala Hart
Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Choba, Port Harcourt, Nigeria.
Oghenefego Michael Adheke *
Department of Human Anatomy, Faculty of Basic Medical Sciences, Southern Delta University, Ozoro, Delta State, Nigeria.
Chidi Onyenaucheya
Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Choba, Port Harcourt, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
The field of histochemistry encompasses a diverse array of techniques designed to detect and visualize specific cellular components. This review systematically categorizes various histochemical methods, including staining techniques, and immunological approaches to identify biomolecules within biological samples. Additionally, this review seeks to buttress the applications of histochemical techniques in aspects of diagnostics, research, and therapeutic monitoring. In trying to understand the current principles and methodologies of histochemistry, researchers can further enhance their ability to interpret the biochemical underpinnings of cellular processes and disease manifestations.
Keywords: Histochemistry, staining, immunological, diagnostics